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Xtandi® Capsules for Prostate Cancer
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Xtandi is an oral androgen receptor inhibitor used for certain stages of prostate cancer. This page explains how it works, who it is for, and how to manage access with US delivery from Canada. It also outlines options for patients evaluating Xtandi price without insurance.
What Xtandi Is and How It Works
Xtandi® contains enzalutamide, a targeted therapy in the androgen receptor inhibitor class. It binds to the androgen receptor, blocks receptor activation, and reduces signaling that can drive prostate cancer growth. It may also prevent the receptor from moving into the cell nucleus and binding DNA. Effects are based on the official product labeling and major clinical trials.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine is taken by mouth and does not require infusion. It is used across several disease states alongside ongoing androgen deprivation therapy when directed by your prescriber.
For background on modern oncology treatments, see our overview in Cancer Drugs List.
Who It’s For
Enzalutamide is approved for adult men with:
- Non-metastatic castration-resistant prostate cancer
- Metastatic castration-resistant prostate cancer
- Metastatic castration-sensitive prostate cancer
It is not indicated for use in women or children. People with a history of seizures or conditions that raise seizure risk should discuss suitability with a healthcare professional. Those with significant liver impairment or prior severe neurologic events need careful evaluation before starting therapy.
Learn more about the condition in our category page for Prostate Cancer.
Dosage and Usage
The typical adult dose is 160 mg once daily, taken at about the same time each day. It can be taken with or without food. Swallow capsules whole; do not open, crush, or chew them. Continue your gonadotropin-releasing hormone therapy if you have not had surgical castration, per label guidance.
General administration tips:
- Take consistently each day, using a reminder or pill organizer.
- If vomiting occurs after a dose, do not take an extra dose that day.
- Keep a simple dosing log to share with your clinician.
Always follow your prescriber’s instructions and the official label for your region.
Strengths and Forms
Commonly supplied presentations include 40 mg capsules. Some markets also have tablet presentations. Availability may vary by region and by supply. Ask our team about current Xtandi 40 mg capsules price.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not take more than the prescribed daily amount.
Storage and Travel Basics
Store at room temperature in the original container with the cap tightly closed. Keep away from moisture. Do not remove the desiccant from the bottle. Keep out of reach of children and pets.
When traveling, keep your medicine in your carry-on bag with the original labeled bottle and a copy of your prescription. For longer trips, pack enough supply plus a small buffer as permitted by your prescriber. Avoid leaving the bottle in a parked car or near heat sources. If your itinerary includes multiple climates, keep the bottle in a protective case and minimize temperature swings.
Benefits
This treatment is designed to block androgen signaling that can drive tumor growth. It can be used across multiple disease settings along with ongoing androgen deprivation therapy. In studies, this class has helped delay disease progression, reduce risk of new metastases in earlier settings, and improve time before chemotherapy is needed. Individual results vary, and monitoring guides whether therapy continues.
Side Effects and Safety
- Fatigue or weakness
- Hot flushes
- High blood pressure
- Headache
- Back or joint pain
- Decreased appetite
- Diarrhea or constipation
- Dizziness or falls
Serious risks can include seizure, posterior reversible encephalopathy syndrome, falls with fractures, ischemic heart disease, and rare allergic reactions. Seek urgent help for fainting, seizure-like activity, chest pain, severe headache, or sudden changes in thinking or vision. Your prescriber may monitor blood pressure and assess fall risk. Report new medicines or supplements before starting them.
Drug Interactions and Cautions
Enzalutamide can interact with a range of medicines. It is a strong inducer of CYP3A4 and can also induce CYP2C9 and CYP2C19, potentially lowering levels of medicines metabolized by these pathways. Caution is needed with drugs that have a narrow therapeutic index, such as warfarin or certain anticonvulsants. Strong CYP2C8 inhibitors (for example, gemfibrozil) may raise enzalutamide exposure; your prescriber will advise if adjustments are appropriate.
Alcohol can increase dizziness or fall risk. Use caution with activities where sudden loss of consciousness would be dangerous. Share a complete list of your prescription drugs, OTC products, and herbal supplements with your healthcare professional.
For broader oncology context, see Common Types Of Cancer.
What to Expect Over Time
Your care team may track symptoms, blood pressure, and lab markers such as PSA. It can take time to assess response, and plans are often individualized. If side effects occur, your prescriber may suggest supportive measures. Staying consistent with daily dosing supports continuity of care. Bring questions to appointments and keep an updated medication list.
Compare With Alternatives
Two other approved oral therapies are commonly considered in similar settings. Abiraterone acetate is taken with prednisone and targets androgen synthesis; see Zytiga®. Darolutamide is another androgen receptor inhibitor with a different interaction profile; see Nubeqa®. Choice depends on your clinical scenario, comorbidities, and prescriber guidance.
Pricing and Access
We support US delivery from Canada. You can review options and discuss Enzalutamide price questions with our pharmacy team before ordering. We aim to provide clear estimates so you can compare options and understand Xtandi Canadian pricing alongside your local pharmacy quotes.
If you use manufacturer support or benefits through your insurer, our team can explain how that may apply. For site savings, check current Promotions. Browse related items within our Cancer category.
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Availability and Substitutions
Supply can vary by market and package size. If your preferred pack is unavailable, your prescriber may recommend a comparable alternative or a temporary substitution that maintains your treatment plan. Contact our pharmacy if you need to coordinate timing or confirm stock, especially when moving between facilities or care settings. If you compare offers, you may also look at Enzalutamide price from Canada across different package counts.
Patient Suitability and Cost-Saving Tips
Not everyone is a candidate for this therapy. Those with uncontrolled hypertension, a history of seizures, or significant liver issues require careful assessment. Your prescriber weighs benefits and risks in the context of your cancer stage and prior treatments.
Cost planning tips:
- Multi-month fills: reduce per-refill fees and simplify adherence.
- Calendar reminders: help you order refills before travel or holidays.
- Paperwork ready: keep your prescription and insurer details available.
- Pharmacy chat: ask about Canadian pricing for enzalutamide and billing steps.
Some patients compare programs or ask about Enzalutamide generic price in markets where generics launch at different times. You can also discuss “cash price” estimates, self-pay options, and approximate cost per month with our team to plan ahead without committing to an order.
Questions to Ask Your Clinician
- Treatment goal: control disease, delay progression, or both
- Appropriate duration: how continuation is evaluated over time
- Monitoring plan: labs, blood pressure, and follow-up visits
- Drug interactions: medicines to avoid or time apart
- Symptom support: managing fatigue, hot flushes, or dizziness
- Activity guidance: driving, operating tools, or fall precautions
Authoritative Sources
FDA DailyMed Prescribing Information
Health Canada Drug Product Database
Astellas Official Product Page
Drug Interactions and Cautions
Additional reading on immunotherapies and supportive options is available in Bavencio Avelumab. This is provided for general education.
Ready to proceed? You can place an order for refill-friendly packs and request pharmacist support. For any final comparisons, our team can discuss Canadian pricing for enzalutamide and assist with documentation.
For patients planning budgets, you can ask about enzalutamide cash price, self pay price, and cost per month. If you use insurance benefits, we can outline whether enzalutamide cost with insurance may change your out-of-pocket responsibilities.
To summarize access, our pharmacy supports predictable steps, clinician-verified prescriptions, and careful coordination if your prescriber adjusts your plan.
Storage and Travel Basics
Before checkout, review your address and travel dates if you will be away. Keep your labeled bottle accessible during trips, and store in a dry place. Do not share your medicine with others.
If you need more context about hormone-related therapies for men, see our article on Mens Health Month for general wellness considerations.
When you are ready, place your order with confidence in our process for US delivery from Canada.
Order from YouDrugstore for prompt shipping with temperature-controlled handling when required and US delivery from Canada. This information is educational and does not replace medical advice from your clinician.
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How does enzalutamide work in prostate cancer?
Enzalutamide blocks signaling through the androgen receptor, which prostate cancer cells often rely on. It prevents androgens from activating the receptor and can inhibit the receptor’s movement into the cell nucleus and its binding to DNA. This reduces transcription of genes that drive tumor growth. It is used across several disease settings, usually with ongoing androgen deprivation therapy. Your prescriber will decide if it fits your treatment plan.
Who should not take this medicine?
It is not indicated for women or children. People with a history of seizures, significant liver problems, uncontrolled hypertension, or conditions that increase fall risk require careful assessment. Tell your prescriber about all medical conditions and medicines. Those taking drugs with a narrow therapeutic index or strong CYP2C8 inhibitors need particular caution due to interactions. Always follow the official label and your clinician’s advice.
What is the usual dose and how should I take it?
The commonly used adult dose is 160 mg once daily. Take it at the same time each day, with or without food. Swallow capsules whole and do not open, crush, or chew them. Continue androgen deprivation therapy if advised by your prescriber. If you miss a dose, take it as soon as you remember the same day. If it is near the next dose, skip the missed dose. Do not take more than prescribed in a 24-hour period.
What side effects are common with enzalutamide?
Frequently reported effects include fatigue, hot flushes, hypertension, headache, joint or back pain, decreased appetite, diarrhea, and constipation. Dizziness and falls can also occur. Serious but less common risks include seizure, PRES, fractures, ischemic heart disease, and allergic reactions. Tell your prescriber about any new or worsening symptoms. Seek urgent care for fainting, chest pain, or neurological symptoms. Monitoring usually includes blood pressure and symptom review.
How should I store the capsules and travel with them?
Store at room temperature in the original bottle with the cap tightly closed. Keep the desiccant inside the bottle and protect from moisture. For travel, keep the labeled container in your carry-on bag with your prescription and prescriber contact details. Avoid heat and direct sunlight, and do not leave the bottle in a parked car. Keep out of reach of children. These are general guidelines; follow your regional label and clinician advice.
Can I take supplements or other medicines with enzalutamide?
Many medicines and supplements interact with enzalutamide. It induces CYP3A4 and can also induce CYP2C9 and CYP2C19, potentially lowering levels of drugs metabolized through those pathways. Strong CYP2C8 inhibitors may increase enzalutamide levels. Share a full list of prescription drugs, OTC products, and herbal supplements with your healthcare professional to assess safety. Do not start or stop anything without checking with your prescriber.
How long will I need to take this therapy?
Duration varies based on disease stage, response, and tolerability. Some patients remain on therapy while the cancer is controlled and side effects are manageable. Your prescriber will review lab results, symptoms, and imaging over time and decide whether to continue or adjust treatment. There is no one-size-fits-all timeline; follow the plan agreed with your clinician.
