Please note: a valid prescription is required for all prescription medication.
Zolmitriptan is a selective serotonin receptor agonist used to treat acute migraine attacks, with or without aura, in adults. It works by narrowing blood vessels in the brain and reducing the release of inflammatory neuropeptides, helping to relieve migraine symptoms such as headache, nausea, and sensitivity to light and sound.
Benefits
- Provides rapid relief from migraine headache pain
- Reduces associated symptoms like nausea and light/sound sensitivity
- Available in multiple formulations: tablet, orally disintegrating tablet, and nasal spray
- Can be taken at the onset of migraine for best results
- May reduce the need for other pain medications during an attack
Dosage
- Initial dose (adults): 2.5 mg by mouth at onset of migraine
- If the headache returns, a second dose may be taken after at least 2 hours
- Maximum dose: 10 mg in 24 hours
- Orally disintegrating tablets can be taken without water
- Nasal spray: typically 2.5 mg in one nostril; may repeat after 2 hours if needed
- Not intended for prevention of migraines—use only during acute attacks
Warnings and Precautions
- Not recommended in patients with coronary artery disease, stroke, or uncontrolled hypertension
- Risk of serotonin syndrome when used with other serotonergic drugs (e.g. SSRIs, SNRIs)
- May cause chest pain, pressure, or tightness—seek medical help if severe
- Use with caution in patients with liver impairment—dose adjustment may be necessary
- Not approved for use in hemiplegic or basilar migraine
- Safety not established for use in children or during pregnancy—use only if clearly needed
Usage Instructions
- Take as soon as migraine symptoms begin
- Do not use more than the prescribed amount
- Do not take more than 10 mg in 24 hours
- Consult a doctor if headaches persist or worsen, or if you need treatment more than 4 times per month
Storage Information
- Store at room temperature between 15°C and 30°C (59°F and 86°F)
- Protect from moisture and heat
- Keep tablets in original packaging until use
- Keep out of reach of children
Common Side Effects
- Dizziness
- Drowsiness or fatigue
- Sensations of tingling, warmth, or pressure
- Dry mouth
- Nausea
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