Zytiga® Tablets for Advanced Prostate Cancer

What Zytiga® Is and How It Works

Zytiga® (abiraterone acetate) is an oral androgen biosynthesis inhibitor used with prednisone for metastatic prostate cancer. It is approved for metastatic castration-resistant and metastatic castration-sensitive disease, alongside ongoing androgen-deprivation therapy. Many people compare Zytiga cost and Zytiga price when choosing between brand and generic abiraterone tablets, and some prefer to buy Zytiga online at Canadian prices.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and prescriptions are reviewed by licensed pharmacists before dispensing. We work with licensed, vetted partner pharmacies worldwide to supply authentic brand medicines, offering a wide selection at budget-friendly pricing.

Abiraterone inhibits the CYP17A1 enzyme, which reduces androgen production in the testes, adrenals, and tumor tissue. Lowering androgen levels helps slow tumor growth and disease progression. Zytiga is taken on an empty stomach and paired with low-dose corticosteroid to reduce mineralocorticoid-related effects. It is not chemotherapy and does not require infusion visits.

Dosage and Usage

• Typical starting dose: 1,000 mg once daily (four 250 mg tablets or two 500 mg tablets), taken on an empty stomach.
• Take at least 1 hour before or 2 hours after food. Food can increase exposure and raise adverse-effect risk.
• Co-administer prednisone as prescribed (commonly 5 mg once or twice daily) and continue androgen-deprivation therapy.
• Swallow tablets whole with water. Do not crush or chew.
• Missed dose: skip and take the next dose at the usual time the following day. Do not double doses.
• Prescribers may adjust dosing with strong CYP3A4 inducers/inhibitors and for liver-function changes.
• Women who are or may become pregnant should avoid handling broken or crushed tablets.

• Store at 15–25°C (59–77°F) in the original container with the lid tightly closed.
• Protect from moisture. Keep out of reach of children and pets.
• For travel, keep tablets in your carry-on with the pharmacy label. Pack enough for your trip plus extra.
• Avoid leaving medicine in hot cars or in direct sun. Aim to keep below 30°C (86°F).
• Do not split tablets to stretch doses. Use the prescribed strength.
• If a tablet breaks, avoid touching fragments with bare hands; discard safely.

Benefits and Savings

Zytiga has demonstrated improvements in overall survival and radiographic progression-free survival in metastatic prostate cancer. It is taken once daily at home, which many patients find convenient. Because it is oral therapy, it reduces infusion visits. It pairs with prednisone to manage mineralocorticoid effects and can be used early or later in the disease course, depending on the clinical plan.

Ordering from Canada can offer significant value. You may see 60–80% savings versus typical US prices, depending on the strength and pack size. Zytiga tablets price can vary by strength; some patients compare Zytiga 500 mg price for fewer tablets per dose, while others review Zytiga 1000 mg cost as the common daily amount. Generic Zytiga cost (abiraterone tablets) is often lower than brand pricing and can reduce your Zytiga cost per month. Multi-month supplies and periodic bulk promotions can further decrease the per-month cost, and reorder reminders help you avoid gaps in therapy.

Zytiga coupon information may appear on our promotions page when available.

Side Effects and Safety

• Common: fatigue, joint swelling or pain, hot flashes, edema, cough, diarrhea, nausea, headache.
• Blood pressure and electrolytes: hypertension and hypokalemia may occur due to mineralocorticoid excess.
• Liver-related: increases in liver enzymes can occur; monitoring is routine.
• Fluid retention: ankle swelling and shortness of breath can happen in susceptible patients.
• Infections: urinary tract and respiratory infections were reported.

Serious effects may include hepatotoxicity, severe hypokalemia with arrhythmias, adrenal insufficiency (especially with infection, stress, or prednisone interruption), and heart failure exacerbation. Abiraterone is not indicated in women or children. It may harm a fetus; pregnant individuals should avoid handling damaged tablets. Drug interactions exist (notably with strong CYP3A4 modulators and CYP2D6 substrates). Regular lab and blood-pressure monitoring is standard.

Onset Time

Biochemical responses, such as a decline in PSA, can begin within several weeks of starting therapy. Imaging responses are typically assessed after a few months. Many patients notice symptom stabilization over 4–8 weeks, though energy and pain changes vary. Survival benefits accrue over months with continuous treatment. Continue therapy as prescribed unless your clinician advises a change based on response or tolerability.

Compare With Alternatives

Several oral androgen receptor pathway inhibitors are used in metastatic prostate cancer. Enzalutamide does not require routine steroids but can cause fatigue and, rarely, seizures. Apalutamide and darolutamide are options in certain settings; each agent has distinct side-effect profiles and interaction considerations.

Chemotherapy, such as docetaxel or cabazitaxel, remains important for selected patients, especially with visceral disease or after progression on hormonal agents. Radium-223 may be considered for symptomatic bone-predominant disease without visceral metastases.

Many patients also compare brand Zytiga with generic abiraterone tablets to balance cost and access. To browse oncology options, see our Cancer category.

Combination Therapy

• Standard: abiraterone plus prednisone with ongoing androgen-deprivation therapy (GnRH agonist/antagonist or post-orchiectomy status).
• Bone health: calcium/vitamin D; bone-modifying agents (e.g., denosumab, zoledronic acid) may be used to lower skeletal-event risk.
• Local therapy: radiation may be used in selected metastatic settings per oncology guidance.
• Sequential therapy: abiraterone is often sequenced with other hormonal agents or chemotherapy based on response and tolerance.
• Monitoring: teams often track liver function, potassium, and blood pressure, and adjust supportive care as needed.

Patient Suitability and Cost-Saving Tips

Zytiga is used in adult men with metastatic castration-resistant or castration-sensitive prostate cancer. It is not for use in women or children. It may be unsuitable for patients with severe hepatic impairment, uncontrolled hypertension, significant fluid retention, or baseline hypokalemia. Close monitoring is important for those with cardiovascular disease or liver test abnormalities.

For affordability, many patients review Zytiga price against generic Zytiga cost. Generic abiraterone can lower ongoing therapy expenses. A longer supply (where prescribed and allowed) can reduce the Zytiga cost per month. You can set simple reorder reminders in your account so you never run out. You may also compare Zytiga 500 mg price when looking to decrease pill count per dose.

You can place your order online or by phone during posted hours. We ship to the US with prompt, express service and provide clear tracking updates. If you have questions about stock or pack sizes, customer-service chat is available during office hours.

Authoritative Sources

ZYTIGA patient information from Janssen

US Prescribing Information for ZYTIGA (Janssen)

Canadian Product Monograph: ZYTIGA (Janssen Canada)

Order Zytiga® from YouDrugstore.com: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is educational and does not replace professional medical advice. Always consult your healthcare provider for diagnosis, treatment decisions, and personalized guidance.