Zytiga® (abiraterone acetate) tablets for advanced prostate cancer

What Zytiga® Is and How It Works

Zytiga® (abiraterone acetate) is an oral androgen biosynthesis inhibitor used with prednisone to treat metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). It is supplied as tablets and is taken once daily on an empty stomach. Patients and caregivers often compare Zytiga cost, Zytiga price, and Zytiga tablets price when planning long-term therapy.

Abiraterone blocks CYP17, an enzyme needed to make androgens in the testes, adrenals, and tumor tissue. Lower androgen levels help slow prostate cancer growth. Treatment continues with ongoing androgen deprivation therapy (ADT) to maintain castrate testosterone levels. Zytiga uses include delaying disease progression and extending survival in appropriate patients, as supported by pivotal trials.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba. Orders are reviewed by licensed pharmacists before dispensing and shipped to the US at Canadian prices. We also partner with licensed, vetted international pharmacies to offer authentic brand medications and a broad selection at affordable pricing.

If clinical questions arise, our pharmacy team can help explain Zytiga prescribing information and safe handling. Friendly customer-service chat is available during posted office hours to assist with ordering and refills.

Dosage and Usage

Typical dosing for adults is 1000 mg once daily, taken as the total daily dose. Zytiga tablet strengths include 250 mg and 500 mg. It is given with prednisone to help reduce mineralocorticoid-related effects.

• mCRPC: abiraterone 1000 mg once daily with prednisone 5 mg twice daily, plus ongoing ADT.
• mCSPC: abiraterone 1000 mg once daily with prednisone 5 mg once daily, plus ongoing ADT.
• Take on an empty stomach. No food for at least 2 hours before and 1 hour after the dose.
• Swallow tablets whole with water. Do not crush or chew.
• Missed dose: take the next dose at the usual time the following day. Do not double up.

Monitoring often includes liver function tests, potassium, blood pressure, and signs of fluid retention. Dose adjustments or treatment holds may be needed for hepatotoxicity or other adverse events. Review all medicines for drug interactions. Abiraterone can affect CYP2D6 and CYP2C8 substrates.

• Storage: store at room temperature (20–25°C). Keep dry and in the original bottle.
• Travel: pack in carry-on luggage, keep in labeled pharmacy packaging, and avoid heat.
• Caregiver handling: pregnant or breastfeeding individuals should avoid handling broken tablets.

Benefits and Savings

Zytiga abiraterone prostate cancer therapy can lower PSA, delay skeletal events, and extend survival in appropriate settings. Once-daily dosing is convenient, and tablets avoid infusion visits. For many families, cost planning matters. Patients compare Zytiga cost per month, Zytiga 500 mg price, and Zytiga 1000 mg cost to choose supply sizes that fit budgets.

Buying from a Canadian pharmacy often brings 60–80% savings versus typical US prices. You can order brand or ask about generic abiraterone tablets when available to reduce Zytiga generic cost. Multi-month supplies can lower the per-month expense.

Side Effects and Safety

Common effects relate to mineralocorticoid excess and liver function changes. Prednisone is co-prescribed to mitigate some reactions. Review the full Zytiga prescribing information and speak with your oncology team about any concerns.

• Common: hypertension, hypokalemia, edema, hot flush, fatigue, joint swelling, cough, diarrhea, UTI, elevated liver enzymes.
• Serious: hepatotoxicity, adrenal insufficiency, severe hypokalemia, fluid overload, arrhythmias, fractures, sepsis.
• Contraindications/precautions: severe hepatic impairment; pregnancy exposure risk; strong CYP3A4 inducers may reduce levels.

Zytiga is not indicated for use in women or children. Use reliable contraception if there is any risk of exposure during handling. Report signs of liver problems, low potassium, or fluid retention promptly.

Onset Time

PSA declines can appear within weeks, though timing varies. Symptom relief, imaging changes, and clinical outcomes may take longer. Ongoing monitoring with labs and scheduled visits helps assess response and guide therapy duration.

Compare With Alternatives

For metastatic prostate cancer, therapy selection is individualized. Abiraterone is one option among androgen receptor pathway inhibitors and chemotherapy.

Enzalutamide is an oral androgen receptor inhibitor used in similar settings. It does not require prednisone, but has its own interaction and side-effect profile. Apalutamide is another oral agent for certain castration-sensitive scenarios. Docetaxel is an IV chemotherapy that may be used upfront in high-volume disease or after progression on hormonal therapy.

YouDrugstore also supplies other oncology medicines for different cancers, such as Xalkori® and Bavencio®. These are for distinct indications and are not substitutes for abiraterone. Discuss the right option for the cancer stage, comorbidities, and treatment goals.

Combination Therapy

Zytiga is used with ongoing ADT and prednisone. In selected patients, clinicians may combine hormonal therapy with local treatments or sequence with chemotherapy. PARP inhibitors can be considered in biomarker-selected prostate cancer. Decisions depend on disease extent, prior therapy, genetics, and tolerance. Follow the plan set by the oncology team.

Patient Suitability and Cost-Saving Tips

Suitable patients include those with mCRPC or mCSPC under specialist care. Caution is needed with liver disease, uncontrolled hypertension, and baseline hypokalemia. Review all medicines and supplements for interactions. The Zytiga drug manufacturer is Janssen; the Zytiga manufacturer maintains patient resources and safety updates for prescribers.

Many shoppers compare Zytiga tablets price, Zytiga cost with insurance, cost of Zytiga with Medicare, and Zytiga cost Medicare versus Canadian pharmacy pricing. When available, generic Zytiga cost (abiraterone) may be lower. Ask about larger fills. Multi-month supplies and bulk promotions often reduce the effective monthly price.

Set reorder reminders so therapy is not interrupted. If you are seeking promotions, see one place for deals and bulk options. View Zytiga coupon information on our promotions page. Some manufacturers also offer programs; terms vary by jurisdiction and coverage. We cannot advise on individual insurance, but our team can outline pharmacy pricing and options.

For related reading on oncology care and side-effect management, see Common Darzalex Side Effects And Tips To Manage Them and Understanding Calquence Medication For Cancer Treatment. Explore our Cancer category for a broader view of treatments carried by our pharmacy.

Authoritative Sources

For full details, review the manufacturer and regulator documents:

Zytiga Official Patient Site (Janssen)

Drugs@FDA: Zytiga Prescribing Information (US)

Health Canada Drug Product Database (search Zytiga)

Order with confidence from YouDrugstore, a licensed Canadian pharmacy. Our pharmacists review prescriptions before dispensing and are available for medication questions. We offer prompt, express, cold-chain shipping to the US, careful packaging, and fair Canadian pricing on brand and generic medicines.

Disclaimer: This page is for general information. It does not replace medical advice. Always follow your prescriber’s directions and the dispensing label. Read the package insert and contact your care team about side effects, interactions, and monitoring.