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Prochlorazine, or Prochlorperazine, is an antipsychotic and antiemetic medicine indicated for psychotic disorders and nausea or vomiting. The tablets are in available in dosage strengths of 5mg and 10mg. Prochlorazine is manufactured by the Toronto-based Apotex, Inc.
Prochlorazine is formulated with prochlorperazine maleate, a phenothiazine that exhibits antipsychotic and antiemetic activities. In addition, it also demonstrates a mild sedative effect. Its mechanism of action has not been fully elucidated, but it is believed to be linked to an altered serotonergic and dopaminergic neurotransmission in the brain.
Prochlorazine is indicated for:
Each pack comes with 100 Prochlorazine tablets.
For psychiatric disorders in adults, patients initially take 10mg 3 or 4 times a day. The dosage will be specific to the condition being treated and the patient’s reaction to treatment.
For nausea and vomiting, adults should take a dose of 5mg to 10mg, 3 or 4 times per day. Alternatively, use a single dose of 5 to 10mg in mild cases. Children should take Prochlorazine in divided doses. For pediatrics, the doctor will determine the dose based on body weight. Prochlorazine is not indicated for pediatrics of less than two years of age, or those who weigh less than 9kg.
Prochlorazine can potentially cause side effects such as:
This list of side effects is by no means exhaustive. You may experience side effects that are not listed above. If you experience unexpected or severe side effects, see a doctor immediately.
The warnings and precautions related to Prochlorazine are listed in the following sections. These may not be a complete list. Read the product leaflet for additional information.
Prochlorazine is contraindicated in patients with:
Frequently asked questions
How to store it
Keep the tablets at a room temperature in a cool, dry place. As with all medicines, keep out of reach of children at all times.
Prochlorazine is also marketed under the generic brand of prochlorperazine.
Previously referred to as paranoid disorder, delusion (or delusional disorder) is a condition in which the patient cannot distinguish between reality and imagination. It is a form of psychosis which involves a misinterpretation of perceptions. Delusions can be either non-bizarre or bizarre. Non-bizarre delusions involve situations that could happen in reality (e.g. being deceived or poisoned) while bizarre delusions involve situations that could not occur in real life (e.g. aliens). Currently there is no way to prevent delusional disorder. However, it is possible to minimize its impact through early diagnosis and appropriate treatment.
Anxiety disorder is an umbrella term that describes a range of psychiatric conditions involving persistent, extreme worry, or fear. It encompasses disorders like panic attacks, panic disorder, social anxiety, disorder agoraphobia, separation anxiety, selective mutism, and generalized anxiety disorder (GAD). If left uncontrolled, anxiety disorder may affect daily functioning, resulting in a lower quality of life.
If you overdose in Prochlorazine, you may experience symptoms such as confusion, muscle stiffness/twitching, difficulty swallowing, fainting, dizziness, and loss of coordination/balance.
In that case, you should call a local Poison Control Center or go to the nearest hospital. You should seek medical help urgently even if you do not experience any of the above symptoms.
If you forget to take a dose, do so as soon as you remember. If it is almost time to take the next dose, you should skip the missed dose and take the next dose as you normally would. Do not take a double dose of Prochlorazine, or else overdose may occur. If you frequently forget to take your tablets, speak with your doctor or pharmacist.