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Zytiga is the trade name of a prescription drug containing Abiraterone as the active component. Zytiga was approved by the FDA in 2011. Abiraterone is often used together with prednisone for the treatment of patients with metastatic prostate cancer (castration resistant prostate cancer) after failing on androgen deprivation therapy. Zytiga is manufactured by Janssen Pharmaceuticals and is available as oral uncoated tablets in a pack size of 120 tablets with the writings AA250 on one side of the tablet. It is a whitish oval tablet.
Abiraterone acetate is an androgen biosynthesis inhibitor which is converted in in the body to abiraterone, which blocks an enzyme (17 α-hydroxylase/C17, 20-lyase) found in the testicles, prostatic and adrenal tumor tissues that is necessary for the production of androgen ( hormone that controls and maintenance the male sexual characteristics). Prostatic carcinoma responds to treatment that reduces androgen levels in the body.
Metastatic prostate cancer
There are no approved generic brands of Zytiga approved by the FDA in USA.
The recommended dose for Zytiga is 1000 mg once daily in combination with 5mg of prednisone twice a day and should be taken on an empty stomach. The tablets should not be chewed or crushed.
Some of the side effects of Zytiga include:
These may not be all the side effects of “Zytiga”.
Do NOT take Zytiga if you:
The use of Zytiga has been associated with Adrenocortical Insufficiency, hence the need to monitor for signs and symptoms in other to made the necessary changes in dosage.
The use of Zytiga has been used has been linked with hypokalemia (low potassium levels), hypertension and fluid retention. Zytiga can increase the mineralocorticoid levels in the body.
The use of Zytiga has been linked with severe hepatic toxicity, acute liver failure, including fulminant hepatitis, and death.
Taking Zytiga with certain drugs can either potentiate their effects in the body or nullify them, it may affect the manner in which these drugs work or vice versa. Therefore you should know the medicines you take and always remember to tell your healthcare provider and pharmacist when you are prescribed new medicine. Below are some examples of medicines that may interact with Zytiga when used together.
This list is not complete so always find out with your doctor if the current medication you taking can interfere with Zytiga.
Zytiga is an FDA approved drug for use in the treatment of metastatic prostate cancer that has spread to other body parts.
Zytiga works by decreasing the production of androgen (male sex hormones) in the body.
Zytiga is used in the treatment of metastatic prostate cancer
NO, there are no generic brands for the oral tablets of Zytiga in the USA.
NO it is not called by a different name.
The recommended dose for Zytiga is 1000 mg once daily in combination with 5mg of prednisone twice a day and should be taken on an empty stomach (do not eat anything for about two hours before taking the tablets and you should not eat anything for about an hour after taking tablets).
The tablets should not be chewed or crushed.
Note: your doctor might recommend a dose different from the above dose, do not try and change the directions issued to you by the doctor.
For the treatment of prostate cancer in men who cannot be treated with other medicines and surgery.
If you accidentally overdose on Zytiga, seek immediate medical advice or call the Poison Helpline at 1-800-222-1222.
Symptoms of over dose in humans is limited, monitor and undergo supportive care such as accessing liver function, cardiac failure and arrhythmias.
This list is not complete therefore you should ask your pharmacist or doctor about possible signs and symptoms of over dosage.
If you miss a dose, skip the missed dose and take your next dose at the regular scheduled time. Do not double up your dose to “catch up”.